Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product. Understanding ADME/Tox is critical for all drug re... Полное описание

This handbook provides an extensive reference source on the materials used in tribological applications. Materials used in tribological applications are, for the most part, common materials used for general engineering applications. Many conventional engineering mate... Полное описание

* Diagrams and illustrations are included in colour to make explanations easier to understand * Ideal for students taking City and Guilds 2357 and 2391 as a companion volume to their textbooks * Up-to-date for the 17th Edition IEE Wiring Regulations Get instant acces... Полное описание

This is the first comprehensive study of the Irish writers of the Victorian age, some of them still remembered, most of them now forgotten. Their work was often directed to a British as well as an Irish reading audience and was therefore disparaged in the era of W.B.... Полное описание

How did the United States become not only the leading contemporary art scene in the world, but also the leading market for art? The answer has to do not only with the talents of American artists or even the size of the American economy, but also--and especially--the ... Полное описание

Over-two thirds of the U.S. population is allergic to poison oak, poison ivy, or a related plant. These and many other common plants in our homes, fields, and gardens are irritants that cause misery to many. But surprisingly, there has never been a general guide to h... Полное описание

This book deals with the end-game for a business. No business entity lasts forever and anyone faced with the task of liquidating a business at the end of its run needs to know that a liquidation doesnt present an insurmountable problem. In fact, substantial value is ... Полное описание

Marine pollution occurs today in varied forms--chemical, industrial, and agricultural-and the sources of pollution are endless. In recent history, weve seen oil spills, untreated sewage, eutrophication, invasive species, heavy metals, acidification, radioactive subst... Полное описание

Scholar, activist and educator Paulo Freire was one of the first thinkers to fully appreciate the relationships between education, politics, imperialism and liberation. This volume is a testament to the works of Paulo Freire in the field of education as well as the l... Полное описание

Performing Brecht is an unprecedented history of the productions of Brecht's plays in Britain over forty years. Margaret Eddershaw surveys all aspects of Brecht in performance, from his methodologies to his place in postmodernist theatre and beyond.She focuses on key... Полное описание

In order to understand the dramatic events of 1989 it is necessary to examine the circumstances leading up to them. The Polish Economic Crisis examines the primary factor. The author analyses how the severe recession of the late 1970s and early 1980s intensified the ... Полное описание

Based on previously unpublished archival records, this book studies the origins of Hong Kong's post war rise to global prominence. It explores the expansion of the gold market, stock market, banking system, foreign exchange market, and insurance in the years 1945-196... Полное описание

Teaching Reading Shakespeare is warmly and clearly communicated, and gives ownership of ideas and activities to teachers by open and explicit discussion. John Haddon creates a strong sense of community with teachers, raising many significant and difficult issues, and... Полное описание

War, Conflict and Human Rights is an innovative new inter-disciplinary textbook, combining aspects of law, politics and conflict analysis to examine the relationship between human rights and armed conflict. Making use of both theoretical and practical approaches, thi... Полное описание

Language skills, study skills, argument skills and legal knowledge are vital to every law student, professional lawyer and academic. Legal Method, Skills and Reasoning suggests a range of 'how-to' techniques for perfecting these academic and practical skills. It expl... Полное описание

This book combines intellectual history with contemporary events to offer a critique of mainstream economic thought and its neoliberal policy incarnation in global capitalism. The critique operates both theoretically, at the level of metaphysics and the philosophy of... Полное описание

Almost 117 million passengers flew on Europe's low cost airlines in 2006. This statistic would have seemed beyond belief in the mid-1980s when air transport was a heavily regulated sphere. This book examines the deregulation which has taken place since then and in pa... Полное описание

This book explains how presidents achieve market-oriented reforms in a contentious political environment. Using an impressive amount of quantitative and qualitative empirical evidence, most of which is reported for the first time, Mejia Acosta argues that presidents ... Полное описание

For the last 60 years, Saudi Arabia has assumed a vital economic role and has been situated on the center stage of the global economic and political scene. While the market was once dominated by American and British firms, and later Japanese corporations, Korean and ... Полное описание

This reference focuses on individualized spinal injury assessments, immobilization techniques, nonoperative and operative indications, operative fixation strategies, and prognoses. Containing over 1900 references, Fractures of the Cervical, Thoracic, and Lumbar Spine... Полное описание

In this critical study, Tidwell examines the conflict of aesthetics and politics in The Diary of Virginia Woolf. As a modernist writer concerned with contemporary aesthetic theories, Woolf experimented with limiting the representative nature of writing. At the same t... Полное описание

Using a wide-ranging variety of texts the author reviews and evaluates a broad range of approaches to textual commentary, introducing the reader to the fundamental distinction between `actual' and `virtual' worlds in critical practice.

This book examines the response of the British Colonial Office to the collapse of belief in racial superiority in the Second World War, and with it the ideological basis of empire. Suke Wolton studies the debate between the Colonial Office and the American State Depa... Полное описание

Drawing on the insights offered by contemporary chaos theory, Narrative Form and Chaos Theory explores how models of turbulent dynamical systems in the physical world parallel structures in certain kinds of narratives. By closely looking at Laurence Sterne?s Tristram... Полное описание

Has black inclusion in the political process changed political institutions and led to more black influence in the governmental process? How do African American legislators balance racial interests with broader issues of government? And how is their effectiveness sub... Полное описание

Economic structuralists use a broad, systemwide approach to understanding development, and this textbook assumes a structuralist perspective in its investigation of why a host of developing countries have failed to grow at 2 percent or more since 1960. Sensitive to t... Полное описание

Known as the New Madrid seismic zone, the Midwestern rift between two geologic plates on the continental US has led many people to believe in strong likelihood of an imminent and hugely destructive earthquake in the Midwest. After the San Francisco earthquake of 1905... Полное описание

Are you looking for more butterflies and birds in your yard? Do you enjoy seasonal color and beauty? Are you concerned about environmental issues such as water conservation and pollution control? Do you yearn for simple, maintenance-free gardening? Arranged in a ques... Полное описание

Being assertive means that you are self-assured know what you want from life, are happy to stand up for yourself and have the respect of those around you. Do you want to be like this? This book will show you how!Practical and easy to read, it looks at what it means t... Полное описание

A quintessentially American epic, Sunnyside stars the one and only Little Tramp, Charlie Chaplin. It's 1916 and, after an extraordinary mass delusion where Chaplin is spotted in more than eight hundred places simultaneously, his fame is at its peak but his inspiratio... Полное описание

This cookbookinspired by the Asparagus Festival in Stockton, Californiapacks new prize-winning recipes plus past festival favorites into this scrumptiously inventive pocket-sized collection. Casual fans are destined to become ardent aficionados of this vitamin-rich, ... Полное описание

Do you feel sluggish or depressed? Do you tire easily? Are you overly sensitive to the cold? Do you feel swollen or overweight? An overactive or underactive thyroid could be the hidden cause behind many of these common symptoms. Left untreated, a malfunctioning thyro... Полное описание

This book provides a simple exposition of the concepts and value-base underpinning community care policy and practice. Written in a jargon-free style, it goes beyond the how-to approach of much of the existing social care literature and examines the princ

Yahoo'snational political columnist and the former chief political correspondent forThe New York Times Magazinebrilliantly revisits the Gary Hart affair and looks at how it changed forever the intersection of American media and politics.In 1987, Gary Hart-articulate,... Полное описание

Constitutive equations define the response of materials which are subjected to applied fields. This volume presents the procedures for generating constitutive equations describing the response of crystals, isotropic and transversely isotropic materials. The book disc... Полное описание

Classification, Parameter Estimation and State Estimation is a practical guide for data analysts and designers of measurement systems and postgraduates students that are interested in advanced measurement systems using MATLAB. 'Prtools' is a powerful MATLAB toolbox f... Полное описание

The use of Bayesian methods for the analysis of data has grown substantially in areas as diverse as applied statistics, psychology, economics and medical science. Bayesian Methods for Categorical Data sets out to demystify modern Bayesian methods, making them accessi... Полное описание

Packed with full-color photographs, this fun and practical guide gives you everything you need to make your relationship with your Boxer even better. Inside, you'll find: Characteristics to look for when choosing a Boxer; a list of supplies you'll need; advice on gro... Полное описание

Standards, technologies, and requirements for computer validation have changed dramatically in recent years, and so have the interpretation of the standards and the understanding of the processes involved. International IT Regulations and Compliance brings together c... Полное описание

This book shows traders how to use Intermarket Analysis to forecast future equity, index and commodity price movements. It introduces custom indicators and Intermarket based systems using basic mathematical and statistical principles to help traders develop and desig... Полное описание

This book is written to give healthcare professionals a comprehensive, understandable and practical text on which to base their care to patients with diabetes whilst in hospital. It gives the conceptual hooks required to be able to understand the principles of diabet... Полное описание

Many people are mortified by their flirting skills and get flustered when dealing with people they're attracted to. This easy-to-follow manual to mastering the art of flirting offers indispensable advice on working the dating scene and reinvigorating your love life. ... Полное описание

MRCOG Short Essay Questions is the essential aid for all trainees studying for the membership examination of the Royal College of Obstetricians and Gynaecologists. This book contains 150 short essay questions, clearly structured to facilitate both learning and practi... Полное описание

As with the beginning of the twentieth century, when food safety standards and the therapeutic benefits of certain foods and supplements first caught the public s attention, the dawn of the twenty-first century finds a great social priority placed on the science of f... Полное описание

A complete, hands-on guide to building Internet voice applications VoiceXML is rapidly becoming the de facto language standard for handling the transition from visual Web browsing to synthesized text-to-speech information access. This book provides Web designers, dat... Полное описание

Joyce Green MacDonald discusses the links between women's racial, sexual, and civic identities in early modern texts. She examines the scarcity of African women in English plays of the sixteenth and seventeenth centuries, the racial identity of the women in the drama... Полное описание

In Eighteenth-Century Fiction and the Law of Property, Wolfram Schmidgen draws on legal and economic writings to analyse the description of houses, landscapes, and commodities in eighteenth-century fiction. His study argues that such descriptions are important to the... Полное описание

Perhaps the most commonly held assumption in the field of development is that middle classes are the bounty of economic modernization and growth. As countries gradually transcend their agrarian past and become urbanized and industrialized, so the logic goes, middle c... Полное описание

This is a practical guide to the medical complications and treatment of anorexia nervosa and related eating disorders. A user-friendly structure allows the reader to access information on the basis of physical complaint (e.g. chest pain) or body system (e.g. neurolog... Полное описание

In this book, Christopher F. Zurn shows why a normative theory of deliberative democratic constitutionalism yields the best understanding of the legitimacy of constitutional review. He further argues that this function should be institutionalized in a complex, multi-... Полное описание

In contrast to most works of international history, which dwell on particular relationships, strategies, wars or crises, the questions in this book are about how diplomacy was actually conducted. The period 1963-76 saw significant changes in diplomatic practice globa... Полное описание

By analysing original sources and evaluating conceptual frameworks, this book discusses the idea proclaimed in the Preamble to the Constitution that Australia is a federal commonwealth. Taking careful account of the influence which the American, Canadian and Swiss Co... Полное описание

In this book, Benoit Dubreuil explores the creation and destruction of hierarchies in human evolution. Combining the methods of archaeology, anthropology, cognitive neuroscience and primatology, he offers a natural history of hierarchies from the point of view of bot... Полное описание

This volume is a project in systematic theology: a rigorous engagement with the Christian tradition in relation to animals under the doctrinal headings of creation, reconciliation and redemption and in dialogue with the Bible and theological voices central to the tra... Полное описание

In this volume Michael D. Matlock analyses five lengthy biblical prose prayers from the exilic and post-exilic period: Solomon's prayer (1 Kings 8.14-61), Ezra's prayer (Ezra 9.5-15), Nehemiah's prayer (Nehemiah 1.4-11), the Levites' prayer (Nehemiah 9.4-37), and the... Полное описание

This is a comprehensive study of the literary function of prayer in Luke-Acts, employing narrative critical methodology and focusing on the theme's relation to Luke's historiographical aims Holmas asserts that the distribution of strategically-placed prayer notices a... Полное описание

The continuing adventures of Rhapsody, The Brother and Grunthor, three of the most engaging characters of modern fantasy, will take the reader ever further into the extraordinarily imagined, complex and exciting world of Elizabeth Haydon's landmark fantasy books. Thi... Полное описание

Each year the average woman spends hundreds of pounds on skincare products, only to be disappointed when the hype outplays the performance. Empowering women to break this cycle, Dr Jessica Wu shares the secrets to transforming your skin from the inside out. Feed Your... Полное описание

Duct Tape: Dream designer material or simple adhesive used for binding purposes? Thanks to Stick It!, duct tape will become a valuable commodity in your house now that it can be coaxed into wacked-out wallets, wild wearables, punked-out paper goods, and funky jewelry... Полное описание

In Xcode 4 Unleashed, renowned Mac/iOS developer Fritz Anderson shows how to use Apple's powerful new Xcode 4 integrated development environment to develop outstanding software with the least effort possible. Anderson demonstrates Xcode 4 by walking through the const... Полное описание

Cohost of The Chew and Food Network Iron Chef Michael Symon shares 120 superfast easy recipes for busy cooks--perfect for weeknights.With his boisterous laugh and Midwestern charm, Michael Symon has become one of the most beloved cooking personalities on television. ... Полное описание

Yes, some women are opting out of their careers, taking an "e;off-ramp,"e; and heading home to raise their babies. But millions of us cannot afford to make that choice. And millions more choose to work because we love our careers. So how are women holding on ... Полное описание

Here is a completely updated edition of the best-selling Resolving Conflicts at Work. This definitive and comprehensive work provides a handy guide for resolving conflicts, miscommunications, and misunderstandings at work and outlines the authors eight strategies tha... Полное описание

Passage Into Discipleship is designed to help older children and youth more faithfully prepare for the act of baptism by teaching what it means to walk a Christian journey. This book incorporates four different learning models that stimulate young people in being exc... Полное описание

Following her wonderful debut, The Still Point, Sackville returns with a strangely beautiful short novel about love and sex and obsession. A literature professor marries his prize student, a woman forty years his junior, and at her request he takes her to the say for... Полное описание