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9 Sato T. et al. Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche. Nature. 2009; 459: 262–265.
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11 Eiraku M. et al. Self-organized formation of polarized cortical tissues from ESCs and its active manipulation by extrinsic signals. Cell Stem Cell. 2008; 3: 519–532.
12 Lancaster M. A. et al. Cerebral organoids model human brain development and microcephaly. Nature. 2013; 501: 373–379.
13 Cepelewicz J. An ethical future for brain organoids takes shape. Quanta Magazine. 2020; January 13 (https://www.quantamagazine.org/an-ethical-future-for-brain-organoids-takes-shape-20200123/).
14 Huh D. et al. Reconstituting organ-level lung functions on a chip. Science. 2010; 328: 1662–1668.
15 McAleer C. W. et al. Multi-organ system for the evaluation of efficacy and off-target toxicity of anticancer therapeutics. Science Translational Medicine. 2019; 11: eaav1386; Edington C. D. et al. Interconnected microphysiological systems for quantitative biology and pharmacology studies. Sci. Rep. 2018; 8: 1–18.
Глава 9. Экосистема внутри вас
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11 О заболеваемости холерой и ее лечении см. статьи на сайтах ВОЗ (https://www.who.int/news-room/fact-sheets/detail/cholera) и Центров по контролю и профилактике заболеваний США (https://www.cdc.gov/cholera/treatment/index.html).
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13 Об экспериментах с холерным вибрионом и его T6SS в моей лаборатории: Logan S. L. et al. The Vibrio cholerae type VI secretion system can modulate host intestinal mechanics to displace gut bacterial symbionts. Proc. Natl. Acad. Sci. 2018; 115: E3779 – E3787.
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20 Cui W. et al. Diverse communities behave like typical random ecosystems. bioRxiv. 2019 (https://doi.org/10.1101/596551); Marsland III R. et al. Available energy fluxes drive a transition in the diversity, stability, and functional structure of microbial communities. PLOS Computational Biology. 2019; 15: e1006793.
