Medications, prescribed by a Doctor or purchased over the counter at a pharmacy, should be safe and effective when used as directed. However, there are cases when complications can arise. Maintaining a proper regimen in managing all details of medications and receiving the intended results can be more difficult than simply popping a pill in the mouth! This ePublication is intended to inform the reader of some details that may not be included on the pill bottle and not detailed by a doctor or pharmacist, but can be important, even critical, to successfully managing medications. This is not a rigorous nor is it a complete discussion of the medication regimen, but rather a primer to alert the reader to be wise when dealing with medications, and to better understand that any medication may have significant risks in addition to significant benefits. The targeted reader is an average adult U.S. citizen.