This book focuses on a prototype of creative causal processes termed BIOS and how the concept can be applied to the physical world, in medicine and in social science. This book presents methods for identifying creative features in empirical data; studies showing biotic patterns in physical, biological, and economic processes; mathematical models of bipolar (positive and negative) feedback that generate biotic patterns. These studies support the hypothesis that natural processes are creative (not determined) and causal (not random) and that bipolar feedback plays a major role in their evolution. Simple processes precede, coexist, constitute and surround the complex systems they generate (priority of the simple). In turn, complex processes feedback and transform simpler ones (supremacy of the complex).Contents:Creative Processes and Mathematical Models:A Research Program: A Science of Creative ProcessesOn the Shoulders of GiantsMathematical Ideas: Bios and Biotic Feedback (with L Kauffman)Methods and Empirical Studies:Bios Data Analysis (with L Carlson-Sabelli, M Patel & A Sugerman)The Biotic Pattern of Heart Rate Variation (with J Messer)The Biotic Expansion of the Universe (with L Kovacevic)Novelty in DNAA Theory of Natural Creation:Bios HypothesisCreation TheoryMathematical GenesisCo-Creation:Biotic Thermodynamics: Entropy as DiversityThe Infinite Attractor of EvolutionBiotic EvolutionBiotic Earth, Biotic ClimateBiotic Processes in EconomicsBiological Priority, Psychological SupremacyCo-Creation Practice: Education, Nursing and Psychodrama (with L Carlson-Sabelli)A Manner of Thinking: Mathematical Priority and Psychological SupremacyIncludes -ROM (with A Sugerman & L Kovacevic)Readership: Researchers in the natural and human sciences interested in the application of mathematical methods and ideas; physicians, economists, sociologists, psychologists, biologists, physicists, applied mathematicians and philosophers of science.