This issue of Sleep Medicine Clinics will be Guest Edited by Jim Barker, MD CPE, FACP, FCCP, FAASM Shirley Fong Jones, MD, FCCP of Scott and White Memorial Hospital and will focus on Obstructive Sleep Apnea. Article topics include Weight loss, Pharmacologic therapy of obstructive sleep apnea, Alternative Therapies, Masks and Interfaces, Outcomes of treatment of hypersomnia for OSA, Effects of therapy on CV outcomes, Complex Sleep Apnea, Oral appliances, Cost of therapy, Medicolegal aspects of treatment, Residual sleepiness, Therapy and Metabolic Outcomes, and Therapies for Children with OSA.