In this collection of essays, several authors, belonging to different generations and philosophical traditions, discuss ample ethical and metaethical issues together with their relations to questions of applied ethics. The volume provides a wide account of some of the main topics in these fields, thus dealing with nearly everything that human beings hold as valuable.Expert scholars and young researchers contribute to this virtual symposium, reframing the current philosophical debates about the definition and the history of the concept of Naturalism, the different declinations of Kantian Constructivism, the functioning of Rational Choice Theory, the complex role played by Neuroscience in redefining the contours of ethical theories and bioethics, the puzzles of Deontic Logic, and the bases of Animal Ethics.Divided into three sections, presented by comprehensive introductions by Sofia Bonicalzi, Leonardo Caffo and Mattia Sorgon, the present collection includes contributions by Martina Belmonte, Michele Borri, Luciana Ceri, Guglielmo Feis, Matteo Grasso, Andrea Lavazza, Sarah Songhorian, and Francesca Vitale. Each author develops a distinctive and independent position, while critically engaging with the central themes of contemporary reflection.This new, major study will benefit moral philosophers, philosophers of science, and scientists concerned with bioethics, while at the same time stimulating and challenging anyone who is curious about the nature and the origins of ethical and metaethical enquiries.