Using the published work of Nobel Laureate Niels Kaj Jerne, this book shows how he developd his ideas. The book is a compilation of his published work, but in fact it is much more than that. Whether the reader wants to read the book systematically, or only browse, it opens a fascinating world of hypotheses, theories, facts and vistas. His selection theory, his view of how immunological diversity is created, and his concept of lymphocytes interacting as a network, reveals Jerne's revolutionary spirit. The book ought to be a rich source of inspiration for everyone interested in science and how science is made.Contents:Preface:The Master and His Atelier (G Stent)Overview:A Portrait of the Immune System (I Lefkovits)On the Writing of a Paper with N K Jerne by Antonio et al.BibliographyFacsimiles of Selected Publications:A Study of Avidity Based on Rabbit Skin Responses to Diphtheria Toxin-Antioxin Mixtures (N K Jerne)The Natural-Selection Theory of Antibody Formation (N K Jerne)Immunological Speculations (N K Jerne)Plaque Formation in Agar by Single Antibody-Producing Cells (N K Jerne & A A Nordin)The Natural Selection Theory of Antibody FormationTen Years Later, in: “Phage and the Origins of Molecular Biology” (N K Jerne)The Somatic Generation of Immune Recognition (N K Jerne)The Immune System (N K Jerne)Towards a Network Theory of the Immune System (N K Jerne)Idiotypic Networks and Other Preconceived Ideas (N K Jerne)The Generative Grammar of the Immune System (N K Jerne)and other papersIntroductions to the BII Annual ReportsHandwritten LettersPostscript (I Lefkovits)Readership: Biological scientists, immunologists and medical doctors.Key Features:Includes contributions by various famous authors and active researchers in the fields of process synthesis, design, modeling and optimizationAddresses the critical issues of energy saving and environmental protectionCovers continuous and batch processesReviews various important techniques for sustainable process design, e.g. process integration (including pinch analysis and mathematical optimization), exergy analysis, life cycle assessment, etc.Bridges between university research and industrial applications