This is a collection of important lecture and original articles and commentaries by Martin Perl, discoverer of the tau lepton and the third generation of elementary particles, and this year's Nobel Prize winner. This book contains a fascinating and realistic picture of experimental science based on the high energy physics research work carried out by him. Using reprints of his articles with his commentaries, the author presents the various aspects of experimental research in science: the pleasures and risks of experimental work; the pain and frustration with experiments that are useless or fail; the dreaming about experiments that were not carried out; the constant search for innovation and creativity in the work; and the special joy of discovery. The articles and commentaries range from the early days of bubble chambers and spark chambers in the 1950's to the author's present research, experiments at an electron-positron collider and a search for free quarks. The book is for the general reader as well as the scientist.Contents:The Discovery of the Tau LeptonThe Physics of the Tau Lepton and Tau NeutrinoInnovations in Experimental Methods and New Directions in PhysicsEssays in PhysicsReflections on Experimental ScienceReadership: General readers interested in science and high energy physicists.Key Features:High quality collection of recent significant advances in bioinformaticsUnique collection of articles on symmetry of genetic code and pattern discoveryWide coverage of bioinformatics applications including computational epidemiologySignificant computational algorithms and statistical analysis of genomic/proteomic data