In September 2008, an international conference on the history of alchemy was held at El Escorial, close to the ancient location of the distilling houses operating under royal patronage during the second half of the 16th century. The present book consists of a selection of the papers presented then, shedding light on little-studied medieval and early modern texts, important alchemical doctrines such as medieval corpuscularianism, early modern spiritus mundi or the function of salt within chymical principles, and discussing such prominent figures as Paracelsus, Isaac Hollandus, Michael Sendivogius, Fontenelle or G. E. Stahl. Last but not least, the book offers new insights on the most recent history of Spanish alchemy.