Since the beginning of the genome project, the necessary involvement of scientists of widely divergent backgrounds has been evident. The proper handling, analysis, dissemination of information, and the control and data gathering of automated process are areas where computers are directly involved. Thus computers are intimately tied into the production and analysis of biological data. However, many challenges lie ahead.This volume is a collection of selected oral and poster presentations given at The Second International Conference on Bioinformatics, Supercomputing and Complex Genome Analysis, organized to address some of these challenges. The topics include the current status and future prospects of genome map, mapping and sequencing, complex genome analysis,linguistic and neural network approaches, database issues, and computer tools in the genome project. The volume will be ideal for students, newcomers, young researchers and experts alike, who are computationally or experimentally oriented.Keynote Speakers: C L Smith, D Grothues, T Ito, T Sano, D Wang, Y-W Zhu, C R Canton & R J Rohins.Contents: The conference consisted of several topical areas and more than fifty talks. The topics covered are: Linguistic ApproachesMapping and Sequencing IGenome MapMapping & Sequencing IIDatabasesApplications of Neural-NetGenome Sequence AnalysisReadership: Biochemists, biologists, computational scientists, geneticists and mathematicians.Key Features:Contains a detailed discussion of arterial guidanceCovers angiogenesis modifiers not discussed in-depth in any other book (semaphorins and nitric oxide synthase)Includes the most recent clinical advances in therapeutic angiogenesis (HGF and HIF)Deals with basic and clinical aspects of anti-angiogenic therapy for cancerDiscusses translational applicationsWritten by leading experts on the most recent emerging topics