Brian Miller, an idealistic young doctor from a wealthy family, opens a clinic in rural Mexico. When a barefoot boy knocks on his door and takes him into the mountains to help a midwife, he is disturbed by the shocking experience. Amid clashing cultures, he searches for the cause of the events he has witnessed and is forced to confront the weakness of science and his own beliefs in explaining such mysteries. His naive investigation leads him further into life-threatening danger. "The Curse" is the tale of this young doctor's journey into the unknown worlds around him and into the even more mysterious world inside himself.