This book presents new insights into the etiology and pathogenesis of systemic diseases recently discovered to be due to specific defects in molecular assemblies, organelles, or other subcellular structures. This new information, of great importance to medical students, physicians, and basic scientists, has not been incorporated into major medical textbooks.The volume will be an important resource for medical or graduate students, investigators and physicians, as it covers major new insights into diverse diseases and concepts missing from pathology textbooks. Each of the eight chapters in the book is written by a leader in the field.Contents:Laminopathies (William T Dauer and Howard J Worman)Inflammasomopathies: Diseases Linked to the NLRP3 Inflammasome (Dominic De Nardo, Johanna Vogelhuber, Larisa Labzin, Pia Langhoff and Eicke Latz)Amyloidosis (Morie A Gertz)Adiposopathy (Harold E Bays and J Michael Gonzalez-Campoy)Telomeropathies (Rodrigo T Calado and Neal S Young)FANC-BLM-Opathies: Recent Progress in the Understanding of Molecular Pathogenesis of Fanconi Anemia and Its Connection with Bloom Syndrome (Toshiyasu Taniguchi, Kiranjit K Dhillon, Maria Castella, Ronald S Cheung and Céline Jacquemont)Lysosomopathies: Pathophysiology and Treatment of Lysosomal Storage Diseases (Beth L Thurberg)Phosphatopathies (Makoto Kuro-o)Readership: Graduate students & researchers in pathology, immunology, cancer research, cell and molecular biology, and pathologists, nephrologists, endocrinologists, immunologists and oncologists.