How do we understand and create kowledge? Does scientific knowledge cover all knowledge? Afrikology tries to answer these questions by tracing the issue of epistemology to the Cradle of Humanity in Africa and through such a reflection the Monograph establishes a basis for holistic and integrated ways of knowledge production that makes it possible to interface scientific knowledge with other forms of knowledge. In this way Afrikology responds to the crisis created by the fragmentation of knowledge through existing academic disciplines. Afrikology therefore advances transdisciplinarity and hermeneutics to a level where they attain a coherent basis for interacting with Afrikology as an epistemology which returns wholeness to understanding and knowledge production.