This second edition of Cost Effectiveness Analysis in Health reviews issues and methods of assessing health care technologies and related programs. It emphasizes methods to perform economic evaluations, such as cost-effectiveness and cost-benefit analysis; methods to assess efficacy, effectiveness, and safety of health care technologies; effectiveness research; and applications to clinical and public policy. The book provides in-depth discussion of the uses and conducting of cost-effectiveness analyses (CEAs) as decision-making aids in public health, health services, and medicine. It explores cost-effectiveness in the context of societal decision making for resource allocation purposes. Chapter topics include: Defining and explaining cost-effectiveness, principles of cost-effectiveness analysis, how to develop a research project, working with costs, probabilities and models, calculating life expectancy, working with health-related quality of life measures, calculating quality-adjusted life years, conducting a sensitivity analysis, preparing your study for publication, working with data, and finding the data you need. For instructors, data sets and other ancillary materials are freely available at http://www.pceo.org/.