A hard-driving movie executive, a beloved soap opera diva, a screenwriter nominated for an Oscar, and a well-known actress married to TV's King of Late Night. Four friends who have led charmed Hollywood lives facing middle age. They have always shared a "Girl's Night Out", but suddenly it becomes a painful vigil as three of the women watch their friend fight for her life in an intensive care unit. She has been attacked by a stalker who is obsessed with all four women. Will the bonds of friendship that have linked them together for years enable them to survive this chilling night?