Life can sometimes thrust us into troubling circumstances that threaten to undo our thin mastery over those things that matter most. In this moving and thought-provoking volume, Arthur Kleinman tells the unsettling stories of a handful of men and women, some of whom have lived through some of the most fundamental transitions of the turbulent twentieth century. Here we meet an American veteran of World War II, tortured by the memory of the atrocities he committed while a soldier in the Pacific. A French-American woman aiding refugees in sub-Saharan Africa, facing the utter chaos of a society where life has become meaningless. A Chinese doctor trying to stay alive during Mao's cultural revolution, discovering that the only values that matter are those that get you beyond the next threat. These individuals have found themselves caught in circumstances where those things that matter most to them--their desires, status, relationships, resources, political and religious commitments, life itself--have been challenged by the society around them. Each is caught up in existential moral experiences that define what it means to be human, with an intensity that makes their life narratives arresting. Their stories reveal just how malleable moral life is, and just how central danger is to our worlds and our livelihood. Indeed, Kleinman offers in this book a groundbreaking approach to ethics, examining "who we are" through some of the most disturbing issues of our time--war, globalization, poverty, social injustice, sex, and religion--all in the context of actual lived moral life. Here then are riveting stories of ordinary men and women, in extraordinary times and threatening situations, making sense of their worlds and facing profound challenges to what matters most in their lives.