Reliability of Large and Complex Systems, previously titled Reliability of Large Systems, is an innovative guide to the current state and reliability of large and complex systems. In addition to revised and updated content on the complexity and safety of large and complex mechanisms, this new edition looks at the reliability of nanosystems, a key research topic in nanotechnology science. The author discusses the importance of safety investigation of critical infrastructures that have aged or have been exposed to varying operational conditions. This reference provides an asymptotic approach to reliability; its methodology, whilst largely mathematical, is designed to help the reader understand and construct general models of large and systems in a wide range of engineering fields. A complete and innovative guide to the reliability of large and complex systemsProvides the reader with a strong foundational knowledge of safety investigation into critical infrastructures; the main research area in the world of safety scienceExplains how to construct large, reliable and safe systems in variable operation conditions