The Second Edition will continue this tradition of better preparing researchers in the basics of pharmacology. In addition, new human interest material including historical facts in pharmacology will be added. A new section on therapeutics will help readers identify with diseases and drug treatments.*Over 30 new figures and tables*More human interest information to provide readers with historical facts on pharmacology research*New section on therapeutics to help identify diseaes and drug treatments*New section on new biological concepts relevant to pharmacological research (i.e., systems biology)*New study sections organized with ASPET and other international pharmacology organizations*New coverage of pharmacokinetics and drug disposition